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Digestion and Obesity

The human body regulates its own weight with great precision. In a lifetime an average person consumes at least 60 million kcal. A gain of 2 stones or 28 lb representing 100,000 kcal involves an error of less than 2 thousandths of one per cent. With this very sophisticated weight management system, how is it that people who want to reduce weight cannot do so?

The answer lies in the interaction of the hormonal control of appetite with the fluids that are produced for digestion in the intestinal tract. We have knowledge of just a few hormones which are produced in the body for digestion. There may be more than a hundred others which are not known. These hormones are very complex, particularly since they nearly all have more than one function.

The whole of the gastro-intestinal tract relies on the production of mucus for protection and lubrication of the epithelial surfaces. The mucus is output from cells through ducts which are havards. The production of mucus is under hormonal control, the hormones being stimulated by both the brain and the digestive organs. If the mucus is overstimulated and the speed of output in the duct increases, then the protective function of the mucus is lost. Now once the overstimulation, the stimulation of appetite in effect, ceases, then the havards producing the mucus should reset to original habituation. But this will not happen if blood glucose is even slightly elevated, as the body will then detect an apparent deficiency in sodium.

The mucus is a vital component of the digestive system. If it is not expressed into the gastrointestinal tract in the right consistency and the right quantity, not only is there poor digestion, but the feedback mechanisms which control hormones do not function. As most people with excess weight have raised blood glucose, it will be seen that they lose control of appetite, the regulator which would otherwise provide fairly precise control of weight. It is obviously unfair to heap blame those who feel impelled to eat more than others. They have a medical problem which is capable of solution.

The first essential for those who wish to reduce weight is to use ActivSignalTM Sodium to signal that there is sufficient sodium in the body environment. This signal will change the mucus producing havards from adverse habituation to original habituation. The mucus will then be restored to its proper function, hormones will feedback to the digestive organs and the brain, and the person will regain appetite control.

The first commercial ActivSignal product is now under development.

Not all the mucus havards will reset to original habituation if blood glucose is even slightly high. There are variations between individuals, but the ideal for avoiding the miliaria class condition of obesity is a liver glucose release set point of 5 mmol/L (90 dl/L). The set point can be measured by getting a reading on one of the low cost electronic blood glucose monitors after an overnight fast of ten hours.

Blood glucose is lowered by a low carbohydrate diet and exercise, such as thirty minutes walking first thing in the morning. Separate meals, of mostly protein and fat, are better than snacking, and a regular eight to ten hour overnight restriction to nothing but water is particularly valuable in getting the set point lower.

In addition to diet and exercise, if necessary, anti-diabetes drugs may be used to lower the blood glucose set point.

Once appetite is established again, then the body will regain shape almost automatically.

Obesity is not the only problem arising from miliaria of the gastrointestinal tract. If the mucus is not protecting the internal surfaces, coupled with inflammation arising from blocked mucus ducts, then there is susceptibility to a number of diseases such as gastritis, peptic ulcer, colitis, irritable bowel syndrome, and bloating. Inflamed areas may acquire an overgrowth of fungus. These, like all miliaria class conditions can now receive prompt and effective treatment with the signalling medicines


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