The human body regulates its own weight with great precision.
In a lifetime an average person consumes at least 60 million kcal.
A gain of 2 stones or 28 lb representing 100,000 kcal involves
an error of less than 2 thousandths of one per cent. With this
very sophisticated weight management system, how is it that people
who want to reduce weight cannot do so?
The answer lies in the interaction of the hormonal control of
appetite with the fluids that are produced for digestion in the
intestinal tract. We have knowledge of just a few hormones which are produced
in the body for digestion. There may be more than a hundred others
which are not known. These hormones are very complex, particularly
since they nearly all have more than one function.
The whole of the gastro-intestinal tract relies on the production
of mucus for protection and lubrication of the epithelial surfaces.
The mucus is output from cells through ducts which are havards.
The production of mucus is under hormonal control, the hormones
being stimulated by both the brain and the digestive organs. If
the mucus is overstimulated and the speed of output in the duct
increases, then the protective function of the mucus is lost.
Now once the overstimulation, the stimulation of appetite in effect,
ceases, then the havards producing the mucus should reset to original
habituation. But this will not happen if blood glucose is even
slightly elevated, as the body will then detect an apparent deficiency
in sodium.
The mucus is a vital component of the digestive system. If it
is not expressed into the gastrointestinal tract in the right
consistency and the right quantity, not only is there poor digestion,
but the feedback mechanisms which control hormones do not function.
As most people with excess weight have raised blood glucose, it
will be seen that they lose control of appetite, the regulator
which would otherwise provide fairly precise control of weight.
It is obviously unfair to heap blame those who feel impelled to
eat more than others. They have a medical problem which is capable
of solution.
The first essential for those who wish to reduce weight is to
use ActivSignalTM Sodium to signal that there is sufficient
sodium in the body environment. This signal will change the mucus
producing havards from adverse habituation to original habituation.
The mucus will then be restored to its proper function, hormones
will feedback to the digestive organs and the brain, and the person
will regain appetite control.
The first commercial ActivSignal product is now under development.
Not all the mucus havards will reset to original habituation
if blood glucose is even slightly high. There are variations between
individuals, but the ideal for avoiding the miliaria class condition
of obesity is a liver glucose release set point of 5 mmol/L (90
dl/L). The set point can be measured by getting a reading on one
of the low cost electronic blood glucose monitors after an overnight
fast of ten hours.
Blood glucose is lowered by a low carbohydrate diet and exercise,
such as thirty minutes walking first thing in the morning. Separate
meals, of mostly protein and fat, are better than snacking, and
a regular eight to ten hour overnight restriction to nothing but
water is particularly valuable in getting the set point lower.
In addition to
diet and exercise, if necessary, anti-diabetes drugs may be used to lower the blood glucose set
point.
Once appetite is established again, then the body will regain
shape almost automatically.
Obesity is not the only problem arising from miliaria of the
gastrointestinal tract. If the mucus is not protecting the internal
surfaces, coupled with inflammation arising from blocked mucus
ducts, then there is susceptibility to a number of diseases such
as gastritis, peptic ulcer, colitis, irritable bowel syndrome,
and bloating. Inflamed areas may acquire an overgrowth of fungus.
These, like all miliaria class conditions can now receive prompt
and effective treatment with the signalling medicines